Polygonum Multiflorum Extract 50% TSG. With high quality and standardised botanical ingredient, The product is produced from the root tubers of Reynoutria multiflora. This high potency preparation contains ≥50% of 2,3,5,4'-tetrahydroxystilbene-2-O-β-D-glucoside (TSG) as shown by HPLC test.
We solve the essential industrial concern of batch to batch variability, providing a predictable yearly supply capacity of 50 tonnes. Further, our extract is processed to reduce hepatotoxic anthraquinones to levels that are safe for long term use. The brown-red powder is more soluble in water than crude materials and can be easily incorporated in different formulation matrices. This product is approved by the FDA and passes stringent quality procedures to provide consistent therapeutic dose for producers producing evidence-based health products.
The special usefulness of stilbene glycoside resides in its bioactivity in several pathways. Unlike common herbal powders, our concentrated extract isolates the major active compound responsible for anti-aging and melanogenesis promoting properties.
TSG acts as an activator of SIRT1, leading to cell longevity pathways. It has excellent antioxidant ability, quenching reactive oxygen species which damage proteins and DNA. The chemical also has neuroprotective properties via inhibiting acetylcholinesterase.
We protect the molecular integrity of this heat sensitive stilbene structure in our extraction technique. Specialised chromatographic procedures lower the emodin content to safe levels and retain the TSG content at appropriate levels. This pharmaceutical grade process means you’re receiving a botanical substance that adheres to the highest international standards.
| Parameter | Specification |
|---|---|
| Appearance | Brown-red fine powder |
| Active Ingredient | 2,3,5,4'-Tetrahydroxystilbene-2-O-β-D-glucopyranoside |
| TSG Content | ≥50% (HPLC verified) |
| Source Material | Root tuber/stem |
| Origin | China |
| Testing Method | High-Performance Liquid Chromatography |
| Heavy Metals | Compliant with international limits |
| Microbiology | Qualified per USP standards |
| Shelf Life | 24 months (proper storage) |
| Certification | FDA registered |
| Annual Capacity | 50 tons (supports large-scale orders) |
We may provide custom specs and concentrations to suit your particular formulation needs, on request.
Cutting-edge Hair Care Technologies: Develop high-end scalp serums and anti-greying solutions at the follicle level. TSG activates MITF (microphthalmia-associated transcription factor), which encourages natural melanin synthesis to prevent premature hair greying.
Cognitive Health Supplements: Formulate neuroprotective nutraceutical capsules and tablets. The high TSG concentration results in significant acetylcholinesterase inhibition, providing cognitive support and shielding neuronal tissues from oxidative harm.
Anti-Aging Skincare Formulations Design innovative cosmetics to fight glycation. Our extract prevents the formation of Advanced Glycation End-products (AGE), keeping collagen and elastin intact for visible anti-aging results.
Liver Support Products Detox recipes using the hepatoprotective qualities. When properly processed like our extract, stilbene glycosides may help liver function without the hazards of raw ingredients.
This Polygonum Multiflorum Extract 50% TSG is easy to put into your manufacturing process whether you’re making hard capsules, powder packets, topical serums, or shampoo formulas.

Your formulations deserve ingredients backed by solid scientific expertise. We draw on 13 years of specialized research in functional nutrition and molecular‑pathway studies.
A core team of four PhDs leads our innovation efforts, supported by 54 filed patents (over 30 granted). We've developed proprietary databases covering six major molecular signaling pathway targets, including Nrf2 and APC research that informs our entire botanical extract portfolio.
Our supply partners maintain GMP, ISO22000, HACCP, and HALAL certifications. Every batch undergoes rigorous testing for heavy metals, microbiology, and active compound verification. You receive not just raw material, but comprehensive technical documentation supporting your regulatory submissions.
We understand the challenges you face—inconsistent supplier quality, unclear safety profiles, inadequate scientific backing. That's why we provide formulation strategy consultation, patent licensing options, and regulatory compliance assistance alongside our premium botanicals.

Q:What specific benefits does Polygonum multiflorum extract provide?
A:The extract supports multiple health dimensions. It demonstrates anti-aging effects by combating cellular oxidation, helping maintain vitality during daily health maintenance. TSG assists liver detoxification processes, particularly beneficial for those with irregular sleep schedules or dietary stress. The immune-modulating properties help regulate systemic responses, though elderly users should consult healthcare professionals before beginning supplementation protocols.
Q:Which product formats work best with this extract?
A:Your options span multiple delivery systems. For convenient daily use, consider capsules or individual powder sachets. Long-term conditioning products benefit from honey pill or granule formats. Hair care applications include shampoo formulations and scalp massage oil blends. Industrial-scale production readily accommodates tablet compression, hard capsule filling, and use as a raw material additive in wash-and-care product lines.
Q:Does topical application pose liver safety concerns?
A:No. Hepatotoxicity risks associated with Polygonum multiflorum stem exclusively from prolonged oral consumption of improperly processed raw material. The skin barrier prevents significant absorption of anthraquinone compounds. Normal topical application in scalp care and cosmetic products creates no hepatic burden, making it suitable for long-term external use in properly formulated products.
Q:How does your 50% TSG extract ensure safety compared to raw herbs?
A:Our specialized purification process reduces emodin and other anthraquinones to levels below 100ppm. This targeted extraction concentrates beneficial stilbene glycosides while removing compounds associated with adverse effects. Combined with HPLC verification of every batch, you receive a pharmaceutical-grade ingredient with a safety profile suitable for commercial health product development.

Contact our technical team at info@extrabroc.com for product specifications, custom concentration options, and sample requests to validate performance in your applications.