Hefei Fushan Yuansheng Biotechnology Co., Ltd. provides pharmaceutical grade L-Ergothioneine 99.9% ultra-high purity sulfur-containing amino acid derivatives for advanced nutraceutical and cosmeceutical applications. Fushan Biotechnology, a national high-tech enterprise, with 54 domestic and foreign innovation patents, over 13 years of functional nutrition specialisation, is the worldwide raw material sales division. We provide premium quality with strict HPLC testing. Our product removes residual fermentation and heavy metal impurities, providing more stability, bioavailability and formulation flexibility than normal 98% pure grades.
The product Rare Master Antioxidant, Manufactured by Advanced Microbial Fermentation or Enzymatic Processes, Pharmaceutical Grade Rather than a typical antioxidant, it uses the OCTN1 transporter system to enter into mitochondria and protect cells in a tailored fashion.
This ultra-pure grade meets the crucial difficulties of the industry. Less pure variations typically include metabolic by products that result in discolouration, off odours or less biological activity. The 99.9% concentration guarantees the highest potency for premium anti-aging, UV protection and therapeutic formulas.
Its unusual thiol-thione tautomerism makes it resistant to autoxidation under physiological settings. This makes it very stable in a wide range of settings and a major benefit for formulators looking for long term product integrity.

L-Ergothioneine 99.9% is a white crystalline powder. The chemical formula is C9H15N3O2S, and the molecular weight is 229.3 g/mol. It shows great water solubility and excellent thermal stability with stability at 80°C even within the pH range of 3.0-9.0.
The 99.9% purity threshold removes residual solvents and heavy metals to meet USP and EP requirements. This delivers more favourable safety profiles for sensitive skin and interior use.
| Items | Specification |
|---|---|
| Appearance | White crystal |
| Active Ingredient | L-Ergothioneine ≥99.9% |
| Test Method | HPLC |
| Shelf Life | 24 months |
| Origin | China |
| Certifications | ISO9001, ISO14001, ISO45001, ISO22000, GMP, KOSHER, HALAL, VEGAN |
L-Ergothioneine 99.9% has become a must-have ingredient in high-end skincare formulas designed to protect against photoaging and antioxidants. Addition of 0.1%–1% may prevent pigmentation efficiently, provide obvious whitening impact and preserve great safety for sensitive skin.
It takes in UV wavelengths near DNA for strong sun protection. When combined with Vitamin C it provides a better anti-inflammatory and healing impact on UV-induced skin irritation.
It stabilises formulations using its natural cell protectant qualities, and enhances absorption of the active. The total antioxidant capacity is increased by synergistic combination with other antioxidants.
Its acceptance in European and US regulatory approvals for maternal and baby formula meals benefits your customers. The high purity grades are gentle enough for use in pregnant women and sensitive populations
It affects cellular redox balance and energy metabolism to promote mitochondrial health and neuronal function. This makes it a great addition to cognitive health and age management solutions.
With our steady supply capability, we can accommodate big volume orders to provide continuous quality for your production schedules.
High-Performance Liquid Chromatography (HPLC) based quality assurance to ensure purity > 99.9%. The inspection processes are rigorous and include:
Optical Rotation Testing: Verifies the L-isomer configuration necessary for biological identification and activity.
Heavy Metal Profiling : Testing using ICP-MS guarantees levels of Lead, Arsenic, Cadmium and Mercury are maintained at 0.1 parts per billion, much below international safety standards.
Residual Solvent Analysis: Headspace GC testing ensures ICH Q3C recommendations compliance and danger of formulation contamination.
Microbial Limits Control: Total Aerobic Microbial Count (TAMC) < 100 cfu/g with absence of pathogenic microorganisms (E. coli, S. aureus).
Stability Assurance: Stability study at 40°C/75% RH indicates the product is stable for 24 months without any deterioration.
Our partner facilities are GMP, ISO22000, HACCP and HALAL certified. The raw materials conform with China New Food Raw Materials, US FDA GRAS, and USP standards.

L-Ergothioneine 99.9% ultra-high purity provides unparalleled formulation flexibility. It is very stable in water systems and does not need additional emulsifiers as required for oil-soluble antioxidants.
Excellent Retinol Compatibility – It Helps Protect The Skin Barrier And Reduce Irritation So Retinol Works Better. Clinical evidence suggests 0.01% to 0.1% doses for maximum outcomes without saturation.
Its capacity to stabilise complicated ingredient matrices is valued by formulators. It controls cellular redox states and prevents degradation of co-formulated actives, therefore increasing product shelf life and sustaining sensory qualities.
Specialised in functional nutrition for 13+ years, with PhD-led R&D and 30+ awarded patents, we do so much more than raw materials. Formulation methods and regulatory compliance, get help with scientific backing.
Standardisation from planting to processing enables us to provide a uniform product. Flexible customisation to satisfy the particular demands of nutraceutical enterprises, functional food brands and cosmeceutical innovators throughout the globe.
Q:Can it give UV protection, anti-inflammatory, and anti-acne effects?
A:Yes, L-Ergothioneine absorbs UV wavelengths close to DNA and provides high-quality sun protection. It heals UV irritation and when taken with Vitamin C it delivers increased anti-inflammatory properties.
Q:What results do the whitening treatments yield?
A:It is safe and non-toxic, and antioxidant-stable. It accumulates in tissues activating cellular antioxidant mechanisms . Cosmetic addition of 0.1-1% suppresses pigmentation and provides apparent whitening.
Q:What are the synergistic effects?
A:As a natural cell protectant, it regulates redox balance and energy metabolism. Addition stabilizes formulations, promotes active ingredient absorption, and strengthens antioxidant capacity when combined with other antioxidants.
Q:What distinguishes product from 98% grades?
A:The 99.9% grade eliminates trace fermentation residues causing off-smells or instability in finished products.
Q:Does it require special storage conditions?
A:Store in a cool, dry place using light-resistant packaging to maintain ultra-high purity over its 24-month shelf life.

Ready to elevate your formulations with ultra-pure L-Ergothioneine 99.9%? Reach out to discuss your requirements: info@extrabroc.com